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Engineering Clostridial Aldehyde/Alcohol Dehydrogenase for Selective Butanol Production

ABSTRACT Butanol production by Clostridium acetobutylicum is accompanied by coproduction of acetone and ethanol, which reduces the yield of butanol and increases the production cost. Here, we report development of several clostridial aldehyde/alcohol dehydrogenase (AAD) variants showing increased bu...

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Hoofdauteurs: Changhee Cho, Seungpyo Hong, Hyeon Gi Moon, Yu-Sin Jang, Dongsup Kim, Sang Yup Lee
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019-02-01
Reeks:mBio
Onderwerpen:
Clostridium acetobutylicum
aldehyde/alcohol dehydrogenase
butanol selectivity
metabolic engineering
protein engineering
Online toegang:https://journals.asm.org/doi/10.1128/mBio.02683-18
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