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Are Inositol Polyphosphates the Missing Link in Dynamic Cullin RING Ligase Regulation by the COP9 Signalosome?

The E3 ligase activity of Cullin RING Ligases (CRLs) is controlled by cycles of neddylation/deneddylation and intimately regulated by the deneddylase COP9 Signalosome (CSN), one of the proteasome lid-CSN-initiation factor 3 (PCI) domain-containing “Zomes” complex. Besides catalyzing the...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xiaozhe Zhang, Feng Rao
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2019-08-01
Rangatū:Biomolecules
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2218-273X/9/8/349
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