Statins suppress cell-to-cell propagation of α-synuclein by lowering cholesterol
Abstract Cell-to-cell propagation of protein aggregates has been implicated in the progression of neurodegenerative diseases. However, the underlying mechanism and modulators of this process are not fully understood. Here, we screened a small-molecule library in a search for agents that suppress the...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2023-07-01
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| Serier: | Cell Death and Disease |
| Online adgang: | https://doi.org/10.1038/s41419-023-05977-9 |
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