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Heme and hemoglobin utilization by Mycobacterium tuberculosis

Iron is essential for growth of Mycobacterium tuberculosis, but most of the iron in the human body is stored in heme within hemoglobin. Here, Mitra et al. identify two heme uptake mechanisms in M. tuberculosis, one dependent on the inner-membrane Dpp importer and the other dependent on host albumin.

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Bibliografische Detailangaben
Hauptverfasser: Avishek Mitra, Ying-Hui Ko, Gino Cingolani, Michael Niederweis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2019-09-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-019-12109-5
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