Comprehensive Essentiality Analysis of the <italic toggle="yes">Mycobacterium tuberculosis</italic> Genome via Saturating Transposon Mutagenesis

ABSTRACT For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studies have analyzed subsaturated libraries, n...

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Autors principals:	Michael A. DeJesus, Elias R. Gerrick, Weizhen Xu, Sae Woong Park, Jarukit E. Long, Cara C. Boutte, Eric J. Rubin, Dirk Schnappinger, Sabine Ehrt, Sarah M. Fortune, Christopher M. Sassetti, Thomas R. Ioerger
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2017-03-01
Col·lecció:	mBio
Accés en línia:	https://journals.asm.org/doi/10.1128/mBio.02133-16
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