APOE4 Drives Sex‐ and Diet‐Dependent Effects on AD‐Like Pathology, Cognition, and Mitochondrial Function

ABSTRACT Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD), yet it's unclear how this allele promotes disease. While factors like diet and sex may modify AD susceptibility in APOE4 carriers, the interaction between these factors is poorly understood. Here, w...

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Bibliografiska uppgifter

Huvudupphov:	Chelsea N. Johnson, Colton R. Lysaker, Xin Cao, Vivien Csikos, Frederick Boakye, Paul J. Kueck, Edziu Franczak, Paige C. Geiger, Jill K. Morris, John P. Thyfault, Heather M. Wilkins
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2026-05-01
Serie:	FASEB BioAdvances
Ämnen:	Alzheimer's disease apolipoprotein E learning memory mitochondria neurodegeneration
Länkar:	https://doi.org/10.1096/fba.2026-00121
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