Integrative multi-omics implicates a CTSB/ITIH-ECM axis in autism spectrum disorder

Background: Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental condition characterized by marked clinical and biological heterogeneity. Despite substantial progress in genetic discovery, the downstream biological mechanisms linking genetic risk to neurodevelopmental pathology re...

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Detalhes bibliográficos

Principais autores:	Guoqi Wang, Gang Zhu, Hongyan Liu, Liuliu Wu, Ziyan Zhang, Ping Pang, Shucheng Si, Guang Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-06-01
coleção:	Neurobiology of Disease
Assuntos:	Autism spectrum disorder Mendelian randomization Therapeutic target Molecular docking Single-nucleus RNA sequencing
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996126001476
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