Integrative multi-omics implicates a CTSB/ITIH-ECM axis in autism spectrum disorder

Background: Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental condition characterized by marked clinical and biological heterogeneity. Despite substantial progress in genetic discovery, the downstream biological mechanisms linking genetic risk to neurodevelopmental pathology re...

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Bibliografiske detaljer

Principais autores:	Guoqi Wang, Gang Zhu, Hongyan Liu, Liuliu Wu, Ziyan Zhang, Ping Pang, Shucheng Si, Guang Yang
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2026-06-01
Serier:	Neurobiology of Disease
Fag:	Autism spectrum disorder Mendelian randomization Therapeutic target Molecular docking Single-nucleus RNA sequencing
Online adgang:	http://www.sciencedirect.com/science/article/pii/S0969996126001476
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