B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer

Abstract Introduction B7-H4 is overexpressed in colorectal cancer (CRC) and plays an important role in tumor growth and immunosuppression. However, the exact mechanism that regulates B7-H4 expression remains largely unknown. Here, we investigated whether protein kinase C δ (PKCδ) regulates the expre...

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Autors principals:	Bin Zhou, Youwei Lu, Zhiming Zhao, Tongguo Shi, Hongya Wu, Weichang Chen, Liang Zhang, Xueguang Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-04-01
Col·lecció:	Cancer Cell International
Matèries:	B7-H4 PKCδ Regulation Metastasis Colorectal cancer
Accés en línia:	https://doi.org/10.1186/s12935-022-02567-1
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