Inference of RNA polymerase II transcription dynamics from chromatin immunoprecipitation time course data.

Gene transcription mediated by RNA polymerase II (pol-II) is a key step in gene expression. The dynamics of pol-II moving along the transcribed region influence the rate and timing of gene expression. In this work, we present a probabilistic model of transcription dynamics which is fitted to pol-II...

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Detalhes bibliográficos

Principais autores:	Ciira wa Maina, Antti Honkela, Filomena Matarese, Korbinian Grote, Hendrik G Stunnenberg, George Reid, Neil D Lawrence, Magnus Rattray
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2014-05-01
coleção:	PLoS Computational Biology
Acesso em linha:	http://europepmc.org/articles/PMC4022483?pdf=render
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