RNAi screen reveals a role of SPHK2 in dengue virus-mediated apoptosis in hepatic cell lines.

Hepatic dysfunction is a feature of dengue virus (DENV) infection. Hepatic biopsy specimens obtained from fatal cases of DENV infection show apoptosis, which relates to the pathogenesis of DENV infection. However, how DENV induced liver injury is not fully understood. In this study, we aim to identi...

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Principais autores:	Atthapan Morchang, Regina Ching Hua Lee, Pa-Thai Yenchitsomanus, Gopinathan Pillai Sreekanth, Sansanee Noisakran, Justin Jang Hann Chu, Thawornchai Limjindaporn
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2017-01-01
Serija:	PLoS ONE
Online dostop:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0188121&type=printable
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