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Repression of ferritin light chain translation by human eIF3

A central problem in human biology remains the discovery of causal molecular links between mutations identified in genome-wide association studies (GWAS) and their corresponding disease traits. This challenge is magnified for variants residing in non-coding regions of the genome. Single-nucleotide p...

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Autores principales: Mia C Pulos-Holmes, Daniel N Srole, Maria G Juarez, Amy S-Y Lee, David T McSwiggen, Nicholas T Ingolia, Jamie H Cate
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications Ltd 2019-08-01
Colección:eLife
Materias:
translation regulation
iron homeostasis
ferritin light chain
iron response protein
eIF3
Acceso en línea:https://elifesciences.org/articles/48193
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