The development of single-domain VHH nanobodies that target the Candida albicans cell surface

ABSTRACT Candida albicans causes life-threatening invasive infections that are hard to diagnose and treat, with drug resistance leading to treatment failure. The goal of this study was to develop VHH (single variable domain on a heavy chain) nanobodies to detect drug-resistant infections. Llamas wer...

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Hlavní autoři:	Giuseppe Buda De Cesare, Frank M. Sauer, Anna Kolecka, Aimilia A. Stavrou, Theo C. Verrips, Teun Boekhout, Edward Dolk, Carol A. Munro
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2024-11-01
Edice:	Microbiology Spectrum
Témata:	antibodies Candida albicans fungal cell wall
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.04269-23
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