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Susceptibility to caspofungin is regulated by temperature and is dependent on calcineurin in Candida albicans

ABSTRACTCandida albicans is a prevalent opportunistic human fungal pathogen. Echinocandins are first-line drugs for the treatment of invasive candidiasis. Molecular mechanisms of resistance to echinocandins have been extensively studied; however, the effect of physiological factors on antifungal eff...

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Hlavní autoři: Lijun Zheng, Yi Xu, Chen Wang, Feng Yang, Yubo Dong, Liangsheng Guo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2023-12-01
Edice:Microbiology Spectrum
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On-line přístup:https://journals.asm.org/doi/10.1128/spectrum.01790-23
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