Multi-omics analysis reveals that CAPG positive macrophages are key immunosuppressive drivers and prognostic determinants in the ferroptosis landscape of hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is characterized by substantial heterogeneity and immune tolerance, and its therapeutic efficacy is profoundly influenced by the immune microenvironment. Ferroptosis, an iron-dependent form of regulated cell death, is closely linked to tumor immune regulation....

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Autors principals:	Xisheng Yin, Yantong Li, Shi Zheng, Chunhui Pan, Zihan Tian, Xiaolin Zhong
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2026-02-01
Col·lecció:	Discover Oncology
Matèries:	Hepatocellular carcinoma Ferroptosis CAPG positive macrophages T cell exhaustion
Accés en línia:	https://doi.org/10.1007/s12672-026-04649-2
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