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Multi-omics analysis reveals that CAPG positive macrophages are key immunosuppressive drivers and prognostic determinants in the ferroptosis landscape of hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is characterized by substantial heterogeneity and immune tolerance, and its therapeutic efficacy is profoundly influenced by the immune microenvironment. Ferroptosis, an iron-dependent form of regulated cell death, is closely linked to tumor immune regulation....

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Autori principali: Xisheng Yin, Yantong Li, Shi Zheng, Chunhui Pan, Zihan Tian, Xiaolin Zhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer 2026-02-01
Serie:Discover Oncology
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Accesso online:https://doi.org/10.1007/s12672-026-04649-2
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