Unraveling the Mechanism of Action, Binding Sites, and Therapeutic Advances of CFTR Modulators: A Narrative Review
Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride and bicarbonate channel localized on the plasma membrane of epithelial cells. Over the last three decades, high-throughput screening assays ha...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2025-02-01
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| Col·lecció: | Current Issues in Molecular Biology |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/1467-3045/47/2/119 |
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