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The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases

Interleukin-17 family (IL-17s) comprises six structurally related members (IL-17A to IL-17F); sequence homology is highest between IL-17A and IL-17F, displaying certain overlapping functions. In general, IL-17A and IL-17F play important roles in chronic inflammation and autoimmunity, controlling bac...

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Principais autores: Victoria Navarro-Compán, Luis Puig, Silvia Vidal, Julio Ramírez, Mar Llamas-Velasco, Cristina Fernández-Carballido, Raquel Almodóvar, José Antonio Pinto, Eva Galíndez-Aguirregoikoa, Pedro Zarco, Beatriz Joven, Jordi Gratacós, Xavier Juanola, Ricardo Blanco, Salvador Arias-Santiago, Jesús Sanz Sanz, Rubén Queiro, Juan D. Cañete
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-08-01
Serier:Frontiers in Immunology
Fag:
IL-17A
IL-17F
IL-23
spondyloarthritis
Th17 cells
MAIT cells
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1191782/full
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