Aptamers Targeting IL17A and Its Receptor Suppress IL17 Signaling in Different Cell Types

<b>Background/Objectives</b>: Interleukin-17A (IL-17A) is a key pathogenic cytokine in autoimmune arthropathies. Current monoclonal antibody inhibitors targeting the IL-17/IL-17RA axis demonstrate clinical efficacy but face significant limitations, including immunogenicity, the loss of therapeutic r...

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Bibliografski detalji

Glavni autori:	Anastasiya Solovieva, Dariya Rippinen, Anna Davydova, Veronika Goncharova, Vladimir Koval, Mariya Vorobyeva, Maksim Korolev
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-01-01
Serija:	Pharmaceuticals
Teme:	interleukin-17A (IL-17A) IL-17 receptor aptamer spondyloarthritis rheumatoid arthritis fibroblast-like synoviocytes
Online pristup:	https://www.mdpi.com/1424-8247/19/2/238
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