Peptide aptamer sP10 targeting NPM1 attenuates liver fibrosis and hepatocellular carcinoma

Abstract Objective Liver fibrosis and hepatocellular carcinoma (HCC) are interrelated diseases with high global mortality rates and limited therapeutic options. This study aimed to develop a dual-targeting therapeutic agent against both fibrogenesis and hepatocarcinogenesis by targeting nucleophosmi...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Xian Feng, Hai-Bin Pang, Yong-Gui Wei, Dong-Hui Xu, Xin-Le Zhu, Dai Cao, Yang Yu, Ya-Fen Chen, Ling Yang, Yu-Jun Zhang, Xiao-Ling Deng, Li-Ping Bai, Kuan-Can Liu, Song-Lin Shi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	Journal of Translational Medicine
Assuntos:	Peptide aptamer Nucleophosmin Liver fibrosis Hepatocellular carcinoma
Acesso em linha:	https://doi.org/10.1186/s12967-026-08144-8
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!