Exploring drug resistance via intercellular crosstalk using spatial transcriptomics in high-grade serous ovarian carcinoma

Abstract Poly(ADP-ribose) polymerase inhibitors (PARPis) have improved the prognosis of patients with high-grade serous ovarian carcinoma (HGSOC). However, PARPis are not effective for all HGSOC patients. Spatial transcriptomics is a powerful tool for characterizing the tumor microenvironment. We us...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Hironori Suzuki, Kosuke Yoshida, Akira Yokoi, Kazuhiro Suzuki, Yuta Hirano, Masami Kitagawa, Eri Asano-Inami, Masato Yoshihara, Yukari Nagao, Satoshi Tamauchi, Nobuhisa Yoshikawa, Hiroaki Kajiyama, Yusuke Yamamoto
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-11-01
Serie:	npj Precision Oncology
Accesso online:	https://doi.org/10.1038/s41698-025-01122-1
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!