Evolutionary Origin of <i>MUTYH</i> Germline Pathogenic Variations in Modern Humans

MUTYH plays an essential role in preventing oxidation-caused DNA damage. Pathogenic germline variations in <i>MUTYH</i> damage its function, causing intestinal polyposis and colorectal cancer. Determination of the evolutionary origin of the variation is essential to understanding the etiological rel...

Descripció completa

Dades bibliogràfiques

Autors principals:	Fengxia Xiao, Jiaheng Li, Philip Naderev Panuringan Lagniton, Si Hoi Kou, Huijun Lei, Benjamin Tam, San Ming Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-02-01
Col·lecció:	Biomolecules
Matèries:	<i>MUTYH</i> pathogenic variant evolutionary origin phylogenic archaeological ancient humans
Accés en línia:	https://www.mdpi.com/2218-273X/13/3/429
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!