Evolutionary Origin of <i>MUTYH</i> Germline Pathogenic Variations in Modern Humans

MUTYH plays an essential role in preventing oxidation-caused DNA damage. Pathogenic germline variations in <i>MUTYH</i> damage its function, causing intestinal polyposis and colorectal cancer. Determination of the evolutionary origin of the variation is essential to understanding the etiological rel...

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Xehetasun bibliografikoak

Egile Nagusiak:	Fengxia Xiao, Jiaheng Li, Philip Naderev Panuringan Lagniton, Si Hoi Kou, Huijun Lei, Benjamin Tam, San Ming Wang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2023-02-01
Saila:	Biomolecules
Gaiak:	<i>MUTYH</i> pathogenic variant evolutionary origin phylogenic archaeological ancient humans
Sarrera elektronikoa:	https://www.mdpi.com/2218-273X/13/3/429
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!