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CD44 Suppression Improved the Chemosensitivity of HT-29 Colorectal Cancer Cells to 5-Fluorouracil and Inhibited Cell Migration

Purpose: CD44 plays a pivotal role through tumorigenesis by regulating cancer cell metastasis, stemness, and chemosensitivity and is considered a promising therapeutic target for human cancers, including colorectal cancer (CRC). Therefore, the present research aimed to examine the simultaneous thera...

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Autors principals: Souzan Najafi, Zohreh Rahimi, Behzad Mansoori, Ali Mohammadi, Fatemeh Mohammadnejad, Mohammad Amini, Ahad Mokhtazadeh, Zahra Asadzadeh, William Chi-Shing Cho, Behzad Baradaran
Format: Artigo
Idioma:Inglês
Publicat: Tabriz University of Medical Sciences 2023-07-01
Col·lecció:Advanced Pharmaceutical Bulletin
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Accés en línia:https://apb.tbzmed.ac.ir/PDF/apb-13-551.pdf
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