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Measurement of synaptic density in Down syndrome using PET imaging: a pilot study

Abstract Down syndrome (DS) is the most prevalent genetic cause of intellectual disability, resulting from trisomy 21. Recently, positron emission tomography (PET) imaging has been used to image synapses in vivo. The motivation for this pilot study was to investigate whether synaptic density in low...

Ausführliche Beschreibung

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Hauptverfasser: Alexandra DiFilippo, Erin Jonaitis, Renee Makuch, Brianna Gambetti, Victoria Fleming, Gilda Ennis, Todd Barnhart, Jonathan Engle, Barbara Bendlin, Sterling Johnson, Benjamin Handen, Sharon Krinsky-McHale, Sigan Hartley, Bradley Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-02-01
Schriftenreihe:Scientific Reports
Online-Zugang:https://doi.org/10.1038/s41598-024-54669-7
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