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Physical activity as a resistance or resilience mechanism in Down syndrome Alzheimer's disease

Abstract INTRODUCTION Adults with Down syndrome (DS) are at risk for Alzheimer's disease (AD). Lifestyle factors such as engagement in moderate‐to‐vigorous physical activity (MVPA) reduce risk or delay the onset of AD. This study aimed to determine whether MVPA confers a resistance (AD pathology) or...

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Principais autores: Victoria L. Fleming, Jamie Peven, Brian C. Helsel, Lauren T. Ptomey, Julianne Clina, Ashlyn Barry, Beau M. Ances, Benjamin L. Handen, Bradley T. Christian, Charles Laymon, Matthew Zammit, Elizabeth Head, Mark Mapstone, Ozioma Okonkwo, Sigan L. Hartley, for the Alzheimer Biomarkers Consortium – Down Syndrome
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-07-01
Serier:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Fag:
Alzheimer Biomarkers Consortium–Down Syndrome
Alzheimer's disease
amyloid beta
cognition
Down syndrome
moderate‐to‐vigorous physical activity
Online adgang:https://doi.org/10.1002/trc2.70127
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