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Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival.

Kaposi's Sarcoma-associated Herpesvirus (KSHV) is the etiologic agent of Kaposi's Sarcoma (KS). KSHV establishes a predominantly latent infection in the main KS tumor cell type, the spindle cell, which is of endothelial cell origin. KSHV requires the induction of multiple metabolic pathways, includi...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Erica L Sanchez, Patrick A Carroll, Angel B Thalhofer, Michael Lagunoff
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-07-01
Schriftenreihe:PLoS Pathogens
Online-Zugang:http://europepmc.org/articles/PMC4510438?pdf=render
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