Identification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug library

Although antibiotic treatment for Lyme disease is effective in the majority of cases, especially during the early phase of the disease, a minority of patients suffer from post-treatment Lyme disease syndrome (PTLDS). It is unclear what mechanisms drive this problem, and although slow or ineffective...

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Autors principals:	Jie Feng, Ting Wang, Wanliang Shi, Shuo Zhang, David Sullivan, Paul G Auwaerter, Ying Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2014-01-01
Col·lecció:	Emerging Microbes and Infections
Matèries:	Borrelia burgdorferi drug discovery FDA approved drug library persisters SYBR Green I
Accés en línia:	https://www.tandfonline.com/doi/10.1038/emi.2014.53
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