The E3 ubiquitin ligase adaptor KLHL8 targets ZAR1 to regulate maternal mRNA degradation in oocytes

Abstract Maternal protein homeostasis and timely degradation of maternal mRNAs are essential for meiotic cell-cycle progression and subsequent embryonic development, but the mechanisms of maternal protein degradation are poorly understood. Here, we show that KLHL8, a substrate adaptor of Cullin-RING...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Huizhen Fan, Ruyi Liu, Ran Yu, Biaobang Chen, Qiaoli Li, Jian Mu, Weijie Wang, Tianyu Wu, Lin He, Lei Wang, Qing Sang, Zhihua Zhang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Springer Nature 2025-07-01
Saila:	EMBO Reports
Gaiak:	KLHL8 Ubiquitination Oocyte Maturation ZAR1 Maternal mRNA Decay
Sarrera elektronikoa:	https://doi.org/10.1038/s44319-025-00537-y
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!