DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer

Decoy technology is a versatile and specific DNA oligonucleotide-based targeting strategy of pathogenic transcription factors (TFs). Chemical modifications of linear decoy oligonucleotides have been made to decrease nuclease sensitivity because of the presence of free ends but at the cost of new lim...

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Principais autores:	Geoffrey Casas, Federico Perche, Patrick Midoux, Chantal Pichon, Jean-Marc Malinge
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-09-01
coleção:	Molecular Therapy: Nucleic Acids
Assuntos:	MT: Oligonucleotides: Therapies and Applications DNA minicircle therapeutic oligonucleotide decoy transcription factor STAT3
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253122001640
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