Q11, a CYP2E1 inhibitor, exerts anti-hepatocellular carcinoma effect by inhibiting M2 macrophage polarization

Abstract Despite significant advancements in cancer immunotherapy, many patients continue to respond poorly. Novel therapeutic strategies and drugs are urgently needed. Here, we found that CYP2E1 is upregulated in M2 macrophages. The CYP2E1 inhibitor, Q11, could inhibit M2 macrophage polarization, w...

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Egile Nagusiak:	Cunzhen Zhang, Yan Fang, Mengxue Guo, Liming Tang, Yurong Xing, Jun Zhou, Yuanyuan Guo, Yuhan Gu, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Springer 2024-12-01
Saila:	Cancer Immunology, Immunotherapy
Gaiak:	Hepatocellular carcinoma CYP2E1 Inhibitor M2 macrophage Metabolites
Sarrera elektronikoa:	https://doi.org/10.1007/s00262-024-03912-1
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