Binding-driven forward tearing protospacer activated CRISPR-Cas12a system and applications for microRNA detection
Abstract CRISPR-Cas12a system, characterized by its precise sequence recognition and cleavage activity, has emerged as a powerful and programmable tool for molecular diagnostics. However, current CRISPR-Cas12a-based nucleic acid detection methods, particularly microRNA (miRNA) detection, necessitate...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2024-11-01
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| Colección: | Journal of Nanobiotechnology |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s12951-024-02915-5 |
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