Effects of Lysine <i>N</i>-ζ-Methylation in Ultrashort Tetrabasic Lipopeptides (UTBLPs) on the Potentiation of Rifampicin, Novobiocin, and Niclosamide in Gram-Negative Bacteria

Outer membrane (OM) drug impermeability typically associated with a molecular weight above 600 Da and high hydrophobicity prevents accumulation of many antibiotics in Gram-negative bacteria (GNB). Previous studies have shown that ultrashort tetrabasic lipopeptides (UTBLPs) containing multiple lysine...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Linus Schweizer, Danyel Ramirez, Frank Schweizer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-03-01
Serie:	Antibiotics
Soggetti:	outer membrane permeabilizer antibiotic potentiator antibiotic adjuvant novobiocin rifampicin niclosamide
Accesso online:	https://www.mdpi.com/2079-6382/11/3/335
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!