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What AlphaFold tells us about cohesin’s retention on and release from chromosomes

Cohesin is a trimeric complex containing a pair of SMC proteins (Smc1 and Smc3) whose ATPase domains at the end of long coiled coils (CC) are interconnected by Scc1. During interphase, it organizes chromosomal DNA topology by extruding loops in a manner dependent on Scc1’s association with two large...

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Bibliografische gegevens
Hoofdauteurs: Kim A Nasmyth, Byung-Gil Lee, Maurici Brunet Roig, Jan Löwe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications Ltd 2023-11-01
Reeks:eLife
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Online toegang:https://elifesciences.org/articles/88656
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