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The role of the glymphatic system in cerebral ischemia: pathological implications and future perspectives

The glymphatic system (GS) consists of a paravascular fluid-exchange network that regulates cerebrospinal and interstitial fluid dynamics, clears metabolic waste, and modulates neuroinflammation. Aquaporin-4 (AQP-4), expressed in astrocytic end-feet, is central to GS function and blood-brain barrier...

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Principais autores: Renata Murguiondo-Pérez, Emilio Moreno-González, Iván Ignacio Mejía, Exsal Manuel Albores-Méndez, Héctor Faustino Noyola Villalobos, Yolanda Cruz Martínez, Antonio Ibarra
Formato: Artigo
Idioma:Inglês
Publicado em: Open Exploration Publishing Inc. 2025-11-01
coleção:Exploration of Neuroprotective Therapy
Assuntos:
aquaporin-4 (aqp-4)
cerebral ischemia
cytotoxic brain edema
glymphatic clearance
neuroinflammation
reperfusion injury
Acesso em linha:https://www.explorationpub.com/uploads/Article/A1004123/1004123.pdf
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