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AAV-Mediated Restoration of Dystrophin-Dp71 in the Brain of Dp71-Null Mice: Molecular, Cellular and Behavioral Outcomes

A deficiency in the shortest dystrophin-gene product, Dp71, is a pivotal aggravating factor for intellectual disabilities in Duchenne muscular dystrophy (DMD). Recent advances in preclinical research have achieved some success in compensating both muscle and brain dysfunctions associated with DMD, n...

Täydet tiedot

Tallennettuna:
Päätekijät: Ophélie Vacca, Faouzi Zarrouki, Charlotte Izabelle, Mehdi Belmaati Cherkaoui, Alvaro Rendon, Deniz Dalkara, Cyrille Vaillend
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2024-04-01
Sarja:Cells
Aiheet:
dystrophin-Dp71
glia
AAV
gene therapy
behavior
brain
Linkit:https://www.mdpi.com/2073-4409/13/8/718
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