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Induction of the ER stress response in NRVMs is linked to cardiotoxicity caused by celastrol

Celastrol is a quinone methide triterpenoid extracted from the root bark of Tripterygium wilfordii Hook F, and it exhibits extensive biological activities such as anti-cancer effects. However, narrow therapeutic window together with undesired side effects limit its clinical application. In this stud...

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Bibliografiske detaljer
Principais autores: Chen Zhong, Zhuang Zhong, Meng Chen, Zhu Zhonghua, Zhang Yin, Zhang Zhao
Format: Artigo
Sprog:Inglês
Udgivet: China Science Publishing & Media Ltd. 2022-08-01
Serier:Acta Biochimica et Biophysica Sinica
Fag:
Online adgang:https://www.sciengine.com/doi/10.3724/abbs.2022104
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