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Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Abstract: Soluble glycoprotein VI (sGPVI) is shed from the platelet surface and is a marker of platelet activation in thrombotic conditions. We assessed sGPVI levels together with patient and clinical parameters in acute and chronic inflammatory conditions, including patients with thermal injury and...

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Autors principals: Samantha J. Montague, Céline Delierneux, Christelle Lecut, Nathalie Layios, Robert J. Dinsdale, Christine S.-M. Lee, Natalie S. Poulter, Robert K. Andrews, Peter Hampson, Christopher M. Wearn, Nathalie Maes, Jonathan Bishop, Amy Bamford, Chris Gardiner, Woei Ming Lee, Tariq Iqbal, Naiem Moiemen, Steve P. Watson, Cécile Oury, Paul Harrison, Elizabeth E. Gardiner
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018-02-01
Col·lecció:Blood Advances
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2473952920311058
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