Recent Advances in the Development of Mammalian Geranylgeranyl Diphosphate Synthase Inhibitors
The enzyme geranylgeranyl diphosphate synthase (GGDPS) catalyzes the synthesis of the 20-carbon isoprenoid geranylgeranyl diphosphate (GGPP). GGPP is the isoprenoid donor for protein geranylgeranylation reactions catalyzed by the enzymes geranylgeranyl transferase (GGTase) I and II. Inhibitors of GG...
Sparad:
| Huvudupphov: | , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
MDPI AG
2017-05-01
|
| Serie: | Molecules |
| Ämnen: | |
| Länkar: | http://www.mdpi.com/1420-3049/22/6/886 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|