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Recent Advances in the Development of Mammalian Geranylgeranyl Diphosphate Synthase Inhibitors

The enzyme geranylgeranyl diphosphate synthase (GGDPS) catalyzes the synthesis of the 20-carbon isoprenoid geranylgeranyl diphosphate (GGPP). GGPP is the isoprenoid donor for protein geranylgeranylation reactions catalyzed by the enzymes geranylgeranyl transferase (GGTase) I and II. Inhibitors of GG...

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Bibliográfalaš dieđut
Váldodahkkit: Staci L. Haney, Veronica S. Wills, David F. Wiemer, Sarah A. Holstein
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2017-05-01
Ráidu:Molecules
Fáttát:
Liŋkkat:http://www.mdpi.com/1420-3049/22/6/886
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