MCC950‐Loaded M12‐Liposome Nanoparticles for Targeted Inhibition of NLRP3 Inflammasome in Sepsis‐Induced Muscle Atrophy

ABSTRACT Background Sepsis‐induced myopathy (SIM) is a severe complication that contributes to late‐stage mortality and functional impairment in sepsis patients. The NLRP3 inflammasome plays a pivotal role in the pathogenesis of SIM, and its selective inhibitor MCC950 has shown promising therapeutic...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Yukun Liu, Kang Wang, Zhikai Xu, Xuan Zhao, Zhanfei Li, Xiangjun Bai, Hao Zhu, Fangli Gao, Liang Zhu, Yuchang Wang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Wiley 2026-04-01
श्रृंखला:	Journal of Cachexia, Sarcopenia and Muscle
विषय:	liposome MCC950 muscle atrophy NLRP3 pyroptosis sepsis
ऑनलाइन पहुंच:	https://doi.org/10.1002/jcsm.70285
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