ARL8B regulates lysosomal function and predicts poor prognosis in hepatocellular carcinoma

Abstract Adenosine 5′-diphosphate ribosylation factor–like 8B (ARL8B), a small GTPase, is involved in lysosome motility. Our study investigates the role of ARL8B in hepatocellular carcinoma (HCC) using in vitro and in vivo experiments, bioinformatics, and clinical data. We found that ARL8B expressio...

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Principais autores:	Liyan Wu, Zelin Weng, Xia Yang, Yuhua Huang, Yansong Lin, Shuo Li, Lingyi Fu, Jingping Yun
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2025-04-01
叢編:	Scientific Reports
主題:	Hepatocellular carcinoma ARL8B Lysosome Immunotherapy Tumor microenvironment Cellular ecosystem
在線閱讀:	https://doi.org/10.1038/s41598-025-97616-w
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