ARL8B regulates lysosomal function and predicts poor prognosis in hepatocellular carcinoma

Abstract Adenosine 5′-diphosphate ribosylation factor–like 8B (ARL8B), a small GTPase, is involved in lysosome motility. Our study investigates the role of ARL8B in hepatocellular carcinoma (HCC) using in vitro and in vivo experiments, bioinformatics, and clinical data. We found that ARL8B expressio...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Liyan Wu, Zelin Weng, Xia Yang, Yuhua Huang, Yansong Lin, Shuo Li, Lingyi Fu, Jingping Yun
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-04-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Hepatocellular carcinoma ARL8B Lysosome Immunotherapy Tumor microenvironment Cellular ecosystem
Онлайн хандалт:	https://doi.org/10.1038/s41598-025-97616-w
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!