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Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases

Modified 2′-deoxyribonucleotide triphosphates (dNTPs) have widespread applications in both existing and emerging biomolecular technologies. For such applications it is an essential requirement that the modified dNTPs be substrates for DNA polymerases. To date very few examples of C5-modified dNTPs b...

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Библиографические подробности
Главные авторы: Claire Dutson, Esther Allen, Mark J. Thompson, Joseph H. Hedley, Heather E. Murton, David M. Williams
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2021-04-01
Серии:Molecules
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Online-ссылка:https://www.mdpi.com/1420-3049/26/8/2250
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