Clinicopathological features of breast cancer in Ukrainian women with BRCA1 c.181T>G (p.Cys61Gly) variant: a case series

IntroductionBRCA1 c.181T>G (p.Cys61Gly) is a pathogenic founder genetic variant prevalent in Central and Eastern Europe. The data on its clinicopathological manifestations in Ukrainian patients remain limited.AimThis study aimed to characterize clinical presentation, tumor biology, and family his...

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Egile Nagusiak:	Nataliya Kitsera, Yaroslav Shparyk, Orest Tril, Ihor Protsko, Ivanna Duda, Olha Oleksyak, Andrii Hrynkiv, Irena Dovhanyk, Iryna Hrytsai, Iryna Tril, Halyna Makukh, Alina Kruhlykova, Denys Kozakov, Sofiia Livshun, Nazarii Kobyliak, Solomiia Sobechko, Myroslava Oliyarnyk, Oksana Sulaieva
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2026-06-01
Saila:	Frontiers in Endocrinology
Gaiak:	BRCA1 breast cancer c.181T>G variant family history germline variant tumor biology
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1859939/full
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