Liposomal UHRF1 siRNA shows lung fibrosis treatment potential through regulation of fibroblast activation
Pulmonary fibrosis is a chronic and progressive interstitial lung disease associated with the decay of pulmonary function, which leads to a fatal outcome. As an essential epigenetic regulator of DNA methylation, the involvement of ubiquitin-like containing PHD and RING finger domains 1 (UHRF1) in fi...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical investigation
2022-11-01
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| Edice: | JCI Insight |
| Témata: | |
| On-line přístup: | https://doi.org/10.1172/jci.insight.162831 |
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