Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion

Abstract Background The biological behavior of epithelial ovarian cancer (EOC) is unique since EOC cells metastasize early to the peritoneum. Thereby, new anti-target agents designed to block trans-coelomic dissemination of EOC cells may be useful as anti-metastatic drugs. The Urokinase Plasminogen...

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Hauptverfasser:	Michele Minopoli, Giovanni Botti, Vincenzo Gigantino, Concetta Ragone, Sabrina Sarno, Maria Letizia Motti, Giosuè Scognamiglio, Stefano Greggi, Cono Scaffa, Maria Serena Roca, Maria Patrizia Stoppelli, Gennaro Ciliberto, Nunzia Simona Losito, Maria Vincenza Carriero
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2019-11-01
Schriftenreihe:	Journal of Experimental & Clinical Cancer Research
Schlagworte:	Formyl peptide receptor Urokinase receptor Peptide Ovarian cancer Adhesion Mesothelium
Online-Zugang:	http://link.springer.com/article/10.1186/s13046-019-1465-8
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