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Conformational stability analyses of alpha subunit I domain of LFA-1 and Mac-1.

β₂ integrin of lymphocyte function-associated antigen-1 (LFA-1) or macrophage-1 antigen (Mac-1) binds to their common ligand of intercellular adhesion molecule-1 (ICAM-1) and mediates leukocyte-endothelial cell (EC) adhesions in inflammation cascade. Although the two integrins are known to have dist...

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Autori principali: Debin Mao, Shouqin Lü, Ning Li, Yan Zhang, Mian Long
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3164198?pdf=render
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