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The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand

The normal function of human intercellular adhesion molecule-1 (ICAM-1) is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). However, ICAM-1 is also used as a receptor by...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Bella, Jordi, Kolatkar, Prasanna R., Marlor, Christopher W., Greve, Jeffrey M., Rossmann, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4140
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