Protective Role of Menthol Against Doxorubicin-Induced Cardiac Injury Through Suppression of TLR4/MAPK/NF-κB Signaling and Oxidative Stress

<b>Background/Objectives</b>: Doxorubicin (DOX) is a highly effective chemotherapeutic agent whose clinical use is limited by dose-dependent cardiotoxicity. This study aimed to investigate the potential protective effects of menthol against doxorubicin-induced cardiotoxicity (DIC) in a rat model. <b...

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Autors principals:	Mona Mansour, Ahmed M. Ashour, Amany M. Gad, Ali Khames, Shaimaa G. Ibrahim, Mohamed H. A. Gadelmawla, Enas S. Gad
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-12-01
Col·lecció:	Pharmaceuticals
Matèries:	menthol doxorubicin cardiotoxicity oxidative stress inflammation TLR4
Accés en línia:	https://www.mdpi.com/1424-8247/19/1/59
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